LATEST NEWS
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Towards targeted-gold nanoparticle enhanced chemoradiation therapy of pancreatic cancer
https://aacrjournals.org/cancerres/issue/82/12_Supplement -
Gene Expression and Early Radiation Response of Two Distinct Neuroblastoma Cell Lines
Abstract Introduction: Neuroblastoma is one of the most common childhood cancers with one of the lowest survival rates, accounting for 15% of childhood cancer mortality. Approximately half of children treated for... -
2-deoxy-D-glucose mitigates Citrobacter rodentium and dibenzazepine-induced gastrointestinal damage and colitis: novel implications of 2-DG polypharmacopea
Abstract Purpose Citrobacter rodentium (CR) infection coupled with blocking Notch/Wnt signaling via γ-secretase inhibitor dibenzazepine (DBZ) disrupts the gastro-intestinal (GI) barrier and induces colitis, akin to ionizing radiation (IR)-induced GI-injury. We investigated... -
Differential expression of deubiquitinating enzymes and its related DNA damage response genes in neuroblastoma heterogeneity
Abstract LB015: Differential expression of deubiquitinating enzymes and its related DNA damage response genes in neuroblastoma heterogeneity Abstract SK-N-AS and SK-N-DZ are two cell lines of pediatric solid tumors neuroblastomas well characterized... -
Technological advancements in cancer diagnostics: Improvements and limitations
https://onlinelibrary.wiley.com/doi/full/10.1002/cnr2.1764 -
Technological Advancements in External Beam Radiation Therapy (EBRT): An Indispensable Tool for Cancer Treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012312/ -
Technological advancements in brachytherapy of cancer
https://onlinelibrary.wiley.com/doi/full/10.1002/cnr2.1764 -
Development of radiation-triggered phosphor platform for localized activation in combinatory cancer treatment (July, 2021)
Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA Abstract A defined spatial and temporal control of induction of toxicity in response to external ionizing radiation such... -
Inhibition of pseudo SARS-CoV-2 binding activity of a anti-cancer polypharmacological agent analogs (July, 2021)
Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA Abstract Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a single-stranded RNA virus with largest genomes (∼ 29,800 bases) of... -
Cloud-based biological domain knowledge derived gene expression classifier to predict the cancer clinical outcome (July, 2021)
Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA Abstract We report the advances of a cloud-based software utilizing advanced algorithms to identify the molecular cancer drivers... -
Modified Sugar a new weapon against COVID-19 (May, 2021)
Modified Sugar a new weapon against COVID-19 2-Deoxy-D-Glucose 2DG, an Adjuvant in COVID-19 Therapy Arsenal. Dr. Rao Papineni lab was the earliest proponent of using 2-DG for polypharmacological action (in lay terms,... -
Overcoming Barriers to Radiopharmaceutical Therapy (RPT): An Overview From the NRG-NCI Working Group on Dosimetry of Radiopharmaceutical Therapy (March, 2021)
Radiopharmaceutical therapy (RPT) continues to demonstrate tremendous potential in improving the therapeutic gains in radiation therapy by specifically delivering radiation to tumors that can be well assessed in terms of... -
Effect of engineered superparamagnetic iron oxide nanoparticles in targeted cardiac precursor cell delivery by MRI (February 2021)
Highlights • The cardiac specific mAb receptors are bound to SPION-PEG micelle through covalent bonding. • The engineered cardiac specific nanoprobe when incubated with the MSCs of stromal vascular fraction yields positively... -
A combinatorial approach of a polypharmacological adjuvant 2-deoxy-D-glucose with low dose radiation therapy to quell the cytokine storm in COVID-19 management (October, 2020)
Abstract COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pandemic disease and is the major cause of deaths worldwide. The clinical complexities (inflammation, cytokine storm, and multi-organ... -
Virtual International Transdisciplinary Conference (VITC-2020) (August 2020)
Virtual International Transdisciplinary Conference (VITC-2020) organized by Department of Physics, School of Advanced Sciences, Vellore Institute of Technology, Vellore - 632 014, TN, India Date: 26th - 28th August 2020 Inauguration Chief Guest... -
Multiple chemical action cancer therapeutics (April, 2020)
Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA Abstract Radiation-produced quasi-free electrons (i.e., low energy electrons in solutions) causes DNA damage. However, there are no evidence... -
The tubercular badger and the uncertain curve:- The need for a multiple stressor approach in environmental radiation protection (January, 2019)
Abstract This article presents the results of a workshop held in Stirling, Scotland in June 2018, called to examine critically the effects of low-dose ionising radiation on the ecosphere. The meeting... -
PACT and Health bags Phase II Small Business Innovation Research award (September, 2019)
For development of I-PARTS integrated platform for anti-cancer radiation therapeutics screening The award was given for the development of anti-cancer agents and radiation modulators screening devices. PACT and Health of Branford,... -
“Cancer Therapy & Radiobiophotonics” with Rao Papineni (June, 2016)
RRS Vodcast interviewing Dr. Rao Papineni on cancer therapy and radiobiophotonics. https://www.youtube.com/watch?v=SbWhUvfmwRY&ab_channel=RadiationResearch -
Clostridium cluster XIVa species an early biomarker in radiation injury (April, 2014)
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Abstract Radiation therapy is being used in the treatment of nearly 60% of the current cancer patients. In spite of the... -
Chemoprevention in Gastrointestinal Physiology and Disease. Natural products and microbiome (July, 2014)
Abstract The human intestinal tract harbors a complex ecosystem of commensal bacteria that play a fundamental role in the well-being of their host. There is a general consensus that diet rich... -
Spot light on intestinal microbiota (August, 2013)
Abstract Microbes in human body play an essential role in immunity, health, and disease. The gut microbes have been found to be the most diverse and constitute the densest cell number... -
Indian scientist gets U.S. patent for cancer treatment (June, 2012)
Nano-particle carries anti-cancer drug and releases it only in the cancerous cell. In what is being considered a path-breaking innovation, a scientist hailing from Hyderabad and his colleagues have invented a...