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Technologies: High-Throughput Integrated Radiation Clonogenic Assay & Spatial Radiation Treatment
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The development of this product was supported through Grant-in-Aid from National Cancer Institute, NCI-SBIR
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Nanomedicine: Radiation activated Photodynamic Cancer Therapy
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The development of this product was supported through Grant-in-Aid from National Cancer Institute, NCI-SBIR
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PH074 Anticancer     PH477 Infection       PH744 Countermeasure
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One-Two Punch Polypharmacological Therapeutics: anticancer, senolytic, & antiviral properties
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AI workflow in Preclinical & Translational Oncology
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Systemic anti-tumor immune response of doped yttria nanoscintillators under low-dose x-ray irradiation  An important development in Combination Cancer therapy! The following article https://www.science.org/doi/10.1126/sciadv.adr4008 is published in a prestigious journal. Taking a challenge from the National Cancer Institute (NCI) at the National Institutes of Health (NIH) to develop innovative vehicles for External Beam Photodynamic Therapy (IXPDT) in cancer treatment,we at Pact and Health were awarded a Grant-in-Aid from NCI-SBIR.

PACT & Health will be presenting two presentations at 2025 AACR Cancer Conference Chicago.

1, CMOS sensor-based micro-dosimetry for radiation theranostics: A novel approach.

2, Elucidating the mechanisms of 2-deoxy-D-glucose (2-DG) and 2-deoxy-D-glucose phoaphate (2-DG-P) in maintaining gastrointestinal homeostasis.

Dr Rao Papineni delivered an invited Talk on “Imaging Molecule to Man: Unveiling the Implications in Low Dose Radiation Research” at the April 2025 NATO Advanced Research meeting in Yerevan, Armenia.

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Dr Rao Papineni will deliver  “Combinatorial energy based cancer therapeutics” at 17th  International Conference for Radiation Research ICRR 2023 Canada.

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International Atomic Energy Agency

Dr Papineni Joined IAEA- NCI  meet from 30 October-1 November 2018 at Vienna establishing a Technical Manual for Intrinsic Radiation Sensitivity assay using clonogenic cell survival (TMIRS). Norms for the Dosimetry and interlaboratory experimentation harmonization.
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A special issue of Translational Cancer Research (TCR) on “Applications of Nanotechnology in Radiation Research”, we showcase the innovative and novel approaches in the utility of nanotechnology in Radiation therapy.

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PACT&Health is Awarded a Prestigious National Cancer Institute  NCI SBIR contract to develop Anti-Cancer Radiation Drug Screening Platform. 
September 2019

PACT&Health is pleased to receive a 1.9 M$ Contract Grant to develop a High-Throughput X-Ray Irradiation Platform to screen novel modulators for Clinical Cancer Radiotherapy. 

"TECHNOLOGIES"

Towards Engineered Precision Assays and Poly Pharmacological Cure-Based Cancer Drug/ Therapy Solutions.

Our Vision

To provide a platform for Cancer Biology, Radiation Oncology, and Radiation Biology for utilizing advanced preclinical and translational technologies in improving biomarker database and impact precision cancer treatment globally.  PACT & Health established in 2013, further focusses in developing Radiation modifying agents such as radiosensitizers and radioprotectants.

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